I agree with Lee. You don't have to wire a patch panel, but installing "home runs" for each stage box does give you the flexibility to grow and add more amplifier channels. The separate runs also mean that if a short develops somewhere, you only lose the connections at one stage box, not all (which is what Dick was getting at).
Make sure you leave a service loop of speaker wire underneath each floor box. If you have to service it later (and you will), you need enough cable to work with so that you're not trying to solder in an impossible location.
Speakon connectors are an excellent idea. Even if your current wedges only have 1/4" jacks, use speakon for all NEW wiring (both under and above the floor) and build speakon-to-1/4" adapters for your old wedges (or actually replace the jacks in the cabinets). Think forward, not backward.