I have found that plugging various home audio components such as CD-players, preamps, amplifiers and the like into different wall receptacles can create all sorts of ground-loop induced hum. And because many (or most) home audio is unbalanced, there's no simple way to do a pin-1 lift to stop these ground loop currents and the hum they create. I've also been able to demonstrate that this ground-loop induced hum can be varied by the amount of current draw from the amplifier(s). So you might not hear any hum when there's no music, but pull a few hundred watts during a big bass note in a song, and all of a sudden you have a 60-Hz modulation hum in your subwoofers during that note. I found this in a pretty exotic home theater system that had "fuzzy bass" and traced the problem back to a copper coax SPDIF cable between a $3,000 CD player and an $8,000 preamp. It wasn't the fault of the inexpensive copper SPDIF cable since the actual ground loop would have happened due to the shield of any interconnecting piece of copper. But when we simply swapped in a piece of TosLink cable that cost less than $5, all the problems went away and the bass sounded perfect. Now I'm pretty sure this wasn't some sort of jitter effect in the SPDIF stream, but was actually caused by ground loop current inside the preamp once the signal was converted to analog.
What this means is that nearly ANY change in the AC power and audio signal path of a home listening system can make some sort of difference in the sound. There's just so many interconnecting paths between all the different pieces of gear, many with potential for shield currents in unbalanced audio.