I agree about the horn and driver synergy. I am shopping for combinations that are "manufacturer recommended' more or less.
One of the front runners right now is the Selenium D220Ti mounted on a Selenium HL14-25.
This is a 45x45 setup. The paperwork from Selenium show a very good Freq response and reasonable narrowing in the UHF range.
This particular design would be 2 Eminence Deltalite 2510's and the above Horn/driver combo mounted in the middle. The idea is to get small and light with reasonable output and cost. This cabinet would be used at least 2 per side with the idea being that the 4 10's would contribute below x-over and above x-over you would have 1 horn. So it's a 90 degree system with 4 10's and 2 1" horns in 2 cabinets. The cabs would be light and easy to get up high on a pole.
Right now this is just one design I'm kicking around. I don't need super high SPL. The goal I'm looking for is lighter weight, easier transport and setup, and good sound quality for a modest price. This is the cheapest priced option I've got so far.
The subs will likely be 218's, but I'm really only concerned with top boxes right now.