If you were going to use it full time, you would build the notebook and accessories into a case, thus avoiding the connection/reconnection. A good notebook case will be foam padded to absorb harmful vibrations from loud music; filtered, ducted supply to the air inlets (fan forced in warm environments)power supply built in with an IEC connector, and in the case of a Martin Lightjockey, space and mounting for your secondary monitor. Also, your system will have a clean windows install with NOTHING but the controller software on it.
The end result will be a bulletproof, reliable and stable system. Realistically, for the cost of a fully equipped Lightjockey, youu couldn't get another system with close to half the features.